Connection | Profiles RNS

Search Result Details

Back to Search Results

This page shows the details of why an item matched the keywords from your search.

Search Results

He, Chuan

One or more keywords matched the following properties of He, Chuan

Property	Value
keywords	DNA methylation
overview	Chuan He is the John T. Wilson Distinguished Service Professor in the Department of Chemistry and Department of Biochemistry and Molecular Biology at the University of Chicago.He received his B.S. (1994) from the University of Science and Technology of China. He received his Ph. D. degree from Massachusetts Institute of Technology in chemistry in 2000. After being trained as a Damon-Runyon postdoctoral fellow at Harvard University from 2000-2002, he joined the University of Chicago as an Assistant Professor, and was promoted to Associate Professor in 2008, Professor in 2010 and John T. Wilson Distinguished Service Professor in 2014. He is also a member of the Cancer Research Center at the University of Chicago. His research spans a broad range of chemical biology, RNA biology, epigenetics, biochemistry, molecular biology, and genomics. His recent research concerns reversible RNA and DNA methylation in biological regulation. His research group discovered the first RNA demethylase and showed that reversible RNA methylation significantly affects gene expression regulation.

Property

Value

keywords

DNA methylation

overview

Chuan He is the John T. Wilson Distinguished Service Professor in the Department of Chemistry and Department of Biochemistry and Molecular Biology at the University of Chicago.He received his B.S. (1994) from the University of Science and Technology of China. He received his Ph. D. degree from Massachusetts Institute of Technology in chemistry in 2000. After being trained as a Damon-Runyon postdoctoral fellow at Harvard University from 2000-2002, he joined the University of Chicago as an Assistant Professor, and was promoted to Associate Professor in 2008, Professor in 2010 and John T. Wilson Distinguished Service Professor in 2014. He is also a member of the Cancer Research Center at the University of Chicago. His research spans a broad range of chemical biology, RNA biology, epigenetics, biochemistry, molecular biology, and genomics. His recent research concerns reversible RNA and DNA methylation in biological regulation. His research group discovered the first RNA demethylase and showed that reversible RNA methylation significantly affects gene expression regulation.

One or more keywords matched the following items that are connected to He, Chuan

Item Type	Name
Concept	DNA Methylation
Academic Article	Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
Academic Article	Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis.
Academic Article	Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing.
Academic Article	Potential functional roles of DNA demethylation intermediates.
Academic Article	Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA.
Academic Article	Nonenzymatic labeling of 5-hydroxymethylcytosine in nanopore sequencing.
Academic Article	Detection of mismatched 5-hydroxymethyluracil in DNA by selective chemical labeling.
Academic Article	Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics.
Academic Article	A non-heme iron-mediated chemical demethylation in DNA and RNA.
Academic Article	Nucleic acid oxidation in DNA damage repair and epigenetics.
Academic Article	Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system.
Academic Article	Decoding the transcriptome and DNA methylome of human primordial germ cells.
Academic Article	High-Resolution Mapping of N6-Methyladenosine in Transcriptome and Genome Using a Photo-Crosslinking-Assisted Strategy.
Academic Article	DNA N(6)-methyladenine: a new epigenetic mark in eukaryotes?
Academic Article	Detecting hepatocellular carcinoma in blood.
Academic Article	Nucleic Acid Modifications in Regulation of Gene Expression.
Academic Article	Characterization of eukaryotic DNA N(6)-methyladenine by a highly sensitive restriction enzyme-assisted sequencing.
Academic Article	A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations.
Academic Article	Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig.
Academic Article	m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.
Academic Article	5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma.
Academic Article	DNA 5-Methylcytosine-Specific Amplification and Sequencing.
Academic Article	N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA.
Academic Article	LEAD-m6 A-seq for Locus-Specific Detection of N6 -Methyladenosine and Quantification of Differential Methylation.
Academic Article	A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation.
Academic Article	Mammalian DNA N6-methyladenosine: Challenges and new insights.
Academic Article	Genome-Wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer's Disease.
Academic Article	Analysis of genome-wide 5-hydroxymethylation of blood samples stored in different anticoagulants: opportunities for the expansion of clinical resources for epigenetic research.
Academic Article	Sequencing of N6-methyl-deoxyadenosine at single-base resolution across the mammalian genome.

Search Criteria

DNA Methylation